1.代表论文(#为并列第一作者,*为通讯作者):
(1) Wang J#, Yan X#, Zhu L#, Liu J, Qiu Y, Li Y, Liu Y, Xue R, Zhan J, Jiang S, Geng Y, Wan Y, Li M, Mao M, Gao D, Yin S, Tong X, Xia J, Ding W, Chen Y, Li J, Zhu C*, Huang R*, Wu C*. Significant histological disease of patients with chronic hepatitis B virus infection in the grey zone. Aliment Pharmacol Ther. 2023, 57(5):464-4742022.
(2) Qian F, Hu S, Zhu Y, Wang Y, Liu J, Qiao J, Shu X, Gao Y, Sun B, Zhu C*. CD56+dimNK Cell is an Important Factor in T Cell Depletion of cART-Treated AIDS Patients. Int J Gen Med. 2022,15:4575-4583.
(3) Zhu L, Li J, Xu J, Chen F, Wu X, Zhu C*. Significance of T-Cell Subsets for Clinical Response to Peginterferon Alfa-2a Therapy in HBeAg-Positive Chronic Hepatitis B Patients. Int J Gen Med. 2022,15:4441-4451.
(4) Wang J#, Zhu L#, Liu L#, Yan X, Xue L, Huang S, Zhang B, Xu T, Ji F, Li C, Ming F, Zhao Y, Cheng J, Chen K, Zhao XA, Sang D, Guan X, Chen X, Yan X, Zhang Z, Liu J, Huang R*, Zhu C*, Wu C*. Clinical features and prognosis of COVID-19 patients with metabolic syndrome: A multicenter, retrospective study. Med Clin (Barc). 2022,158(10):458-465.
(5) Li W#; Yu X#; Chen X#; Wang Z; Yin M; Zhao Z; Zhu C*; HBV induces liver fibrosis via the TGF-β1/miR-21-5p pathway, ExpTher Med, 2021, 21(2):169.
(6) Chen X#;Xu Y#;Tu W#; Huang F#;Zuo Y; Zhang HG; Jin L;Feng Q;Ren T; He J; Miao Y; Yuan Y; Zhao Q; Liu J; Zhang R; Zhu L;Qian F;Zhu C;Zheng H*; Wang J*; Ubiquitin E3 ligase MID1 inhibits the innate immune response by ubiquitinating IRF3,Immunology, 2021,doi: 10.1111/imm.13315. Epub ahead of print.
(7) Ding Y#; Liu K#;Xu Y#; Zhao Q; Lou S; Xiang X; Yan L; Cao Z;Xie Q;Zhu C*;Bao S*; Wang H*; Combination of inflammatory score/liver function and AFP improves the diagnostic accuracy of HBV-related hepatocellular carcinoma,Cancer Med, 2020, 9(9):3057-3069.
(8) Zhang HG#;Guo J#; Yuan Y;Zuo Y; Liu J; Zhu L; Miao Y; Chen X; Jin L; Huang F;Ren T; He J; Shi W; Wen Z;Zhu C*;Zheng H*; Dong C*;Qian F*; Ubiquitin E3 Ligase c-Cbl Is a Host Negative Regulator of Nef Protein of HIV-1,Front Microbiol, 2020, 11:597972.
(9) Jin Liu#;Lincong Jin#; Xiangjie Chen; Yukang Yuan; YiboZuo; Ying Miao; QianFeng; Hongguang Zhang;Fan Huang;TingtingGuo;Liting Zhang; Li Zhu; FengQian; Chuanwu Zhu;HuiZheng*; USP12 translocation maintains interferon antiviral efficacy by inhibiting CBP acetyltransferase activity,PLoS Pathogens, 2020, 16(1), e1008215.
(10) Wang J#; Huang R#; Yan X; Li M; Chen Y; Xia J; Liu Y; Jia B; Zhu L; Zhang Z; Zhu C*; Wu C*; Red blood cell distribution width: A promising index for evaluating the severity and long-term prognosis of hepatitis B virus-related diseases,Dig Liver Dis, 2020, pii: S1590-8658(20)30001-3.
(11) Cao Z#; Liu Y#; Wang S#; Lu X; Yin S; Jiang S; Chen L;Cai M;Zeng B; Yao Y; Tang W; Zhao G; Xiang X; Wang H;Cai W;Zhu C*; Li H*;Xie Q*; The impact of HBV flare on the outcome of HBV-related decompensated cirrhosis patients with bacterial infection,Liver Int, 2019, 39(10):1943-1953.
(12) Wang J#; Zhang Z#; Yan X; Li M; Xia J; Liu Y; Chen Y; Jia B; Zhu L; Zhu C*; Huang R*; Wu C*;Albumin-Bilirubin (ALBI) as an accurate and simple prognostic score for chronic hepatitis B-related liver cirrhosis,Dig Liver Dis, 2019, 51(8):1172-1178.
(13) Yan L#; Zhu C#; Li J#; Chen L; Ding Y; Cao Z; Liu K; Lin L; Tang W; Xie Q; Xu Y; Bao S*; Wang H*; Entecavir add-on or switch-to pegylated interferon improves HBsAg clearance in HBe antigen negative chronic hepatitis B patients,Infect Drug Resist, 2018, 11:2001-2009.
(14) Chen L#; Zhu C#; Li F#; Wang Y; Bao R; Cao Z; Xiang X; Yan L; Lin L; Zhao G; Xie Q*; Bao S*; Wang H*; Correlation between hepatic human males absent on the first (hMOF) and viral persistence in chronic hepatitis B patients, Cell Biosci, 2018, 8:14.
(15) Cao Z#; Li Z#; Wang Y#; Liu Y; Mo R; Ren P; Chen L; Lu J; Li H; Zhuang Y; Liu Y; Wang X; Zhao G; Tang W; Xiang X; Wang H; Cai W; Liu L; Zhu C*;Bao S*; Xie Q*; Assessment of serum Golgi protein 73 as a biomarker for the diagnosis of significant fibrosis in patients with chronic HBV infection, J Viral Hepat, 2017, 24 suppl 1:57-65.
(16) Xu P#; Guo A; Xu J; Yao J; Chen H; Wang F; Zhu C*;Evaluation of a combinational use of serum microRNAs as biomarkers for liver diseases,Clin Res HepatolGastroenterol, 2017, 41(3):254-261.
(17) Li W#; Zhu C#; Wu Y#; Wang Z; Zhu C*;Increased Pygo2 expression in liver of patients with hepatitis B virus-related fibrosis,Liver Int, 2015, 35(12):2522-2529.
(18) Chuanwu Z*; Feng Q; Ming L; Haiyan W; Huan F; Xiangrong L; Xuehua Z; Xiang Z; Xiujuan S; Ping X; Detection of telomerase reverse transcriptase mRNA in peripheral blood mononuclear cells of patients with liver failure, Hepat Mon, 2014,14;14(4):e17976.
(19) Zhu CW*;Chen M;Luo XR; Wang HY; Wang LH; Wu JH; Li M; Zhang XH; Zhu W; Ye JZ;Qian F; Interferon alpha on expression of hTERT mRNA in peripheral blood mononuclear cells of patients with chronic hepatitis B, ClinDevImmunol, 2011, 2011:920146.
2.主要承担的科研项目:
主持项目
(1)国家自然科学基金委员会,面上项目,82172252,HBsAg泛素化降解的机制及其与抗病毒应答关系的研究,2022-01-01 至 2025-12-31,54万元,在研,主持
(2)江苏省科技厅,面上项目,BK20211080,HBsAg泛素化降解的机制及其与抗病毒应答关系的研究,2021-07-01 至 2024-06-30,10万元,在研,主持
(3)苏州市科学技术局,关键技术项目,SKY2021059,生物型人工肝技术在HBV相关肝功能衰竭治疗中的应用研究,2021-07至2024-06,20万元,在研,主持
(4)苏州市卫健委,姑苏卫生人才计划项目,GSWS2020091,乙型肝炎病毒包膜蛋白HBsAg泛素化降解的机制研究,2021-01-01至2023-12-31,85万元,在研,主持
(5)苏州市科学技术局,关键技术项目,SS202068,基于个体化的乙型肝炎病毒母婴传播阻断技术的优势及其应用研究,2020-07至2023-06,10万元,在研,主持
(6)苏州市科学技术局,社会发展项目,SYS2019110,Tim-3靶向治疗对慢性乙型肝炎患者精准临床治愈的作用及其机制研究,2019-07至2022-06,5万元,在研,
主要参加
(6)江苏省科技厅项目:BK20180212,外泌体源性ANXA2 分子经由ERK 通路调控肝癌侵袭转移机制的研究,2018/07-2021/07,10 万元,结题,主要参加
(7)苏州市临床重点病种技术专项:LCZX201613,苏州市乙肝病毒母婴传播精准阻断技术的研究,2016/11-2019/12,30万元,结题,主持
(8)国家科技部“十二五重大专项”:2014ZX10005001,中医药联合恩替卡韦治疗乙肝肝硬化的临床研究,2014/01-2016/12,20.77万,结题,分中心主持
(9)苏州市临床重点病种技术专项:LCZX201315,外周血和PBMCs中hTERT mRNA定量检测技术在肝衰竭预后评估中的应用,2013/11-2016/12,30万元,结题,主持
(10)江苏省科技厅项目:BL2013017,以POLA和酵母重组新技术对我国HIV-1流行株新耐药突变位点的研究,2013/07-2016/06,50万元,结题,主要参加
(11)苏州市科学技术局项目:SYS201156,苏州市艾滋病患者抗反转录病毒治疗前后HIV-1耐药性及敏感性的研究,2011/07-2014/07,4万元,结题,主要参加
(12)苏州市科学技术局项目:SYS201058,肝衰竭患者血清端粒酶逆转录酶定量检测对疗效和预后的评估价值,2010/08-2013/08,4万元,结题,主持
(13)苏州市科学技术局项目:SYS2008036,苏州市HIV-1流行株基因型及其对药物敏感性的研究,2008/08-2011/08,4万元,结题,主持
(14)国家科技部“十一五重大专项”:2008ZX10201,乙型病毒性肝炎疫苗免疫策略和新型疫苗的研究,2008/10-2010/12,15 万元,结题,分中心主持
(15)苏州市科学技术局项目:2002019,慢性乙型肝炎患者外周血树突状细胞的功能对干扰素疗效的影响,2002/01-2004/12,3万元,结题,主持
(16)江苏省卫生厅项目:H200149,干扰素治疗与慢性乙肝肝细胞癌变相关因素关系的研究,2002/01-2004/12,16 万元,结题,主持
3.获奖情况及学术报告:
科研奖励
(1)朱传武(2/3).苏州市卫健委,苏州市新技术引进二等奖,2018 年,应用酵母菌重组和HIV 克隆系统对苏州市HIV-1感染者抗逆转录病毒药物敏感性和耐药性的表型和基因型研究(钱峰,朱传武,朱莉).
(2)朱传武(3/3).苏州市卫健委,苏州市新技术引进一等奖,2017年,B7-H 家族在感染性疾病诊疗中的应用(胥萍,徐俊驰,朱传武).
(3)朱传武(1/5).苏州市科技局,苏州市科技进步三等奖,2016 年,端粒酶活性定量检测对肝衰竭预后的评估价值(朱传武,王海燕,李明,钱峰,罗湘蓉).
(4)朱传武(1/3).江苏省卫健委,江苏省新技术引进二等奖,2015 年,端粒酶活性定量检测技术在肝衰竭预后评估中的应用(朱传武,李明,钱峰).
(5)朱传武(3/3).苏州市卫健委,苏州市新技术引进二等奖,2015年,外周血淋巴细胞PD-1/PD-L1检测在感染性疾病诊疗中的应用(胥萍,徐俊驰,朱传武).
(6)朱传武(1/4).苏州市卫健委,苏州市新技术引进一等奖,2014 年,端粒酶活性定量检测技术在肝病治疗中的应用(朱传武,李明,钱峰,王海燕);
(7)朱传武(1/6).苏州市科技局,苏州市科技进步二等奖,2006 年,慢性乙型肝炎外周血树突状细胞的功能与干扰素疗效的研究(朱传武,钱峰,王海燕,李明,常建国,张雪华);
(8)朱传武(2/3).江苏省卫生厅,江苏省新技术引进一等奖,2005 年,CEQ8000 DNA 测序技术在肝脏病中的应用(童福易,朱传武,胥萍);
(9)朱传武(1/6).江苏省卫生厅,江苏省新技术引进二等奖,2005 年,树突状细胞功能检测在慢性乙型肝炎抗病毒治疗中的应用(朱传武,钱峰,王海燕,李明,张雪华,罗湘蓉);
(10)朱传武(1/4).苏州市科技局,苏州市科技进步二等奖,2004 年,乙肝病毒前C 区基因变异的研究(朱传武,孙颐,李明,钱峰)。
学术报告
(1)学术报告,2023年,Zhu Chuanwu, Ubiquitin E3 Ligase β-TrCP Negatively Regulates Hepatitis B Surface Protein of HBV, the 32nd Conference of the Asian Pacific Association for the Study of the Liver (APASL 2023), Taipei International Convention Center,15-19 February 2019.
(2)学术报告,2020年,朱传武,乙型肝炎病毒母婴传播的个体化免疫预防策略10年数据分析,2020年中华医学会肝病学分会学术年会,线上会议,于2020年9月7-13日.
(3)学术报告,2019年,Zhu Chuanwu, Hepatitis B virus related liver failure management, the 28th Annual Conference of the Asian Pacific Association for the Study of the Liver (APASL 2019), Philippine International Convention Center, 19-24 February 2019.
4.学术任职:
(1)中华医学会感染病学分会产科感染学组委员
(2)中国脂肪性肝病诊疗协作组委员
(3)中国医师协会整合医学分会整合感染病防控与管理专业委员会常务委员
(4)江苏省医学会感染病学分会副主任委员
(5)江苏省中西医结合学会肝病专业委员会副主任委员
(6)江苏省中西医结合学会感染病专业委员会副主任委员
(7)苏州市中西医结合学会肝病专业委员会主任委员
(8)苏州市医学会肝病专业委员会、感染病专业委员会名誉主任委员
5.杂志编委:
Journal of Public Health and Epidemiology、World Journal of Virology、international journal of general medicine、Journal of viral hepatitis、European Journal of Gastroenterology & Hepatology、中华医学杂志(英文版)、世界华人消化杂志、临床肝胆病杂志、抗感染药学等期刊编委或审稿专家。